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Triple Negative Breast Cancer Survival Rate

Triple negative breast cancer is a type of breast cancer that is very aggressive and generally develops and spreads more rapidly as compared to other forms of breast cancer. This is the reason why it has a lower rate of survival in comparison to other forms of breast cancer

Triple negative breast cancer indicates that the human epidermal growth factor receptor 2 (Her-2), the progesterone receptor (PR) and the estrogen receptor (ER) were all negative. Nearly ten to twenty percent of all breast cancers are of this type.

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Symptoms of triple negative breast cancer

It has similar symptoms as those elicited by most forms of breast cancer. They include:

  • Dimpling of the breast. Changes in shape and size of the affected breast
  • A particular area of the breast may become thicker. A painless lump may be present
  • The nipple may turn inwards. It may peel or flake along with the breast skin
  • The skin of the breast may have ridges running through it
  • Pus-like or bloody discharge from the nipple
  • Increased redness and tenderness of the breasts and the nipples
  • There may be unintended loss of weight, ulcers of the skin, bone pain and inflammation of the arm beside the affected breast

Causes of triple negative breast cancer

  • Excessive growth of hormone receptors in the breasts results in development of abnormal cells which leads to triple negative breast cancer. The exact cause for this is unknown.
  • Excessive years of menstruation caused due to late menopause and/or early menstruation; exposure to certain chemicals and radiation; family history of breast cancers, etc can increase the risk to developing triple negative breast cancer

Treatment of triple negative breast cancer

  • Surgery to remove the tumor or the affected breast
  • Radiation therapy to direct extreme rays of radiation at the cancer cells to destroy them
  • Chemotherapy to intravenously administer special cancer killing drugs

Survival rate for triple negative breast cancer

The survival rate for triple negative breast cancer refers to the percentage of people who survive the disease for a particular period of time after the detection of the condition. The five year survival rate is the most followed standard which indicates the survival of the patients for at least a period of five years after initial diagnosis.

  • The prognosis for triple negative breast cancer is really poor and it is the worst among all types of breast cancers.
  • One study has found that the status of androgen receptor and the lymph node, and the size of tumor are very good outlook markers for nearly 16.3 percent of the patients affected by triple negative breast cancer
  • Another study found that HER-1 over-expression, lymph node status and the tumor size are associated with poor prognosis and survival rate
  • The reoccurrence for triple negative breast cancer is quick and generally results in a fatality after a five year period
  • The overall five year survival rates for triple negative breast cancer was around 79.6 percent and tumor-free survival rate was about 77.9 percent
  • The overall ten year survival rates for triple negative breast cancer was around 63.15 percent; tumor-free survival rate was about 62.87 percent and P53-positive expression rate was about 71 percent

It is important to note that the survival rate for triple negative breast cancer cannot be generalized as each individual case is unique and is dependent on several factors such as the age of the patient, the overall health, etc.

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